There is not much information about Brusaferro's life. The date of birth is deduced from the Rollo of all the painters of the Collegio novo of 1726, in which we read that he was forty-two years old, resident in San Giovanni Decollato, without children or even assistants.
Girolamo Brusaferro attended Niccolò Bambini's school in his youth, where he learned the rules of good painting. He then followed the path of Sebastiano Ricci and finally developed his own style, somehow translating the two masters.